FREE AT LAST?
NEW CGRP BLOCKING DRUGS PREVENT
MIGRAINE ATTACKS FOR MOST.
Now a new class of experimental drugs designed specifically for migraine is one of the biggest breakthroughs, giving migraine sufferers hope. The drugs are aimed at a compound called calcitonin gene-related peptide or CGRP.
The drugs block the activity of the CGRP, which spikes during migraine attacks. CGRP is "the best validated target for migraine, ever," says Dr. David Dodick, a neurologist at the Mayo Clinic.
Four different companies are testing drugs that affect CGRP: Alder Pharmaceuticals, Amgen, Eli Lily and Company, and Teva Pharmaceuticals. They hope to build an injectable CGRP blocker in the next two years.
Over half of patients are seeing a 50% reduction in migraine frequency while using the CGRP drugs — some even more. Dr. Peter Goadsby, Director of the UCSF Headache Center in San Francisco, called it "a truly landmark development" that will offer many patients "freedom from the daily grind of being a migraine sufferer." Dr. Richard Lipton, Director of the Einstein College of Medicine in New York, told NBC News, "I think that these are truly designer drugs for migraine."
The CGRP monclodal antibodies are the first mechanism-based specific anti-migraine preventative treatment ever developed. Several years ago we saw development of triptans. They are migraine-specific treatments for acute attacks. These new drugs are designed to prevent the attacks from occurring. With this, for the first time, doctors will give migraine patients a migraine drug for prevention.
Dr. Goadsby states, "They're preventative medications. They'll reduce the frequency and they'll reduce the severity [of migraine attacks], and it looks like they're going to do it with virtually no side effect penalty."
39% of migraine patients are eligible for preventative migraine treatment, but less than half receive a preventative treatment.
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I've suffered from migraines and abdominal migraines for 9 years. No medication or prior treatments helped me until coming to see Dr. Stratford, MD. This procedure has 100% given me my life back. I couldn't be more thankful for him and this procedure.